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Bio & Medicine

A new diagnostic platform employs nanotechnology and machine intelligence to rapidly identify infectious diseases.

Irresistible illnesses and respiratory contaminations, specifically, are the main sources of worldwide mortality. Accordingly, there is a pressing requirement for fast, huge-scope indicative apparatuses that can identify these infections early, something that doesn’t at present exist. To resolve these issues, McGill College Teacher of Bioengineering Sara Mahshid’s lab has fostered an across-the-board location stage (QolorEX) that can convey test results in only 13 minutes.

For use where individuals gather, like clinics, schools, and air terminals, the tests are directed by taking a spit test (no swabs required) and moving it to a microfluid gadget, which then utilizes AI to take tiny pictures of the example naturally. Those pictures are sent off to a cellphone application that deciphers the information into an experimental outcome.

“Our lab aims to build portable, low-cost technologies with practical clinical results for use in low-resource settings, at-home, or communal environments,” say Mahshid and her students, Ph.D. candidates Tamer Abdel Fatah and Mahsa Jalali, co-authors of a recent Nature Nanotechnology paper.

“This platform, shown to have a 95% accuracy rate on par with quantitative PCR when it comes to COVID testing using saliva samples, is potentially a valuable tool for “Mahshid, who is also the Canada Research Chair in Nano-Biosensing Devices, adds that because it is accessible, more tests can be done. This could lead to an early diagnosis that could save lives and stop the spread of respiratory diseases around the world.”

More information: Tamer AbdElFatah et al, Nanoplasmonic amplification in microfluidics enables accelerated colorimetric quantification of nucleic acid biomarkers from pathogens, Nature Nanotechnology (2023). DOI: 10.1038/s41565-023-01384-5

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