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Biochemistry

Biochemistry

The first experimental confirmation that certain microorganisms are powered by electricity

Alcohol is made, for instance, by microorganisms using CO2 and electricity in microbial electrosynthesis. However, up until this point, it has only been hypothesized how this process functions biologically. It has now been demonstrated experimentally for the first time by researchers at the Leibniz Institute for Natural Product Research and Infection Biology (Leibniz-HKI) that the bacteria can produce more chemicals than previously thought by utilizing electrons from hydrogen. Their exploration has been published in the journal Green Science. A promising technology in light of climate change and the energy transition is microbial electrosynthesis. It has the ability to bind carbon
Biochemistry

Nanomicelles of artificial spherical chromatophore for selective CO2 reduction in water

Scientists led by Prof. Tian Jia from the Shanghai Organization of Natural Science of the Chinese Foundation of Sciences have fostered another system for noticeable light-initiated specific carbon dioxide (CO2) change by copying the vital components and gathering designs of regular photosynthetic purple bacterial chromatophores through supramolecular self-get-together. On May 18, this work was published in Nature Catalysis. It provides new insights for accurately simulating the biological structures and functions of supramolecular assemblies as well as energy conversion for artificial photosynthesis. Photosynthesis is the definitive wellspring of energy and natural matter for essentially all living organic entities. In nature, photosynthetic
Biochemistry

Researchers construct a mosquito testing arena to learn how mosquitos find us across vast distances.

We know a lot about how mosquitoes like to be near us, but how do they find us from up to 100 meters away? Utilizing an ice-arena estimated outside testing field in Zambia, scientists observed that human stench is basic for mosquitoes looking for conduct over significant distances. The team also found specific body odor components that can be carried in the air. This could help explain why some people are more attracted to mosquitoes than others. The work appears on May 19 in Current Science. Most investigations of mosquito inclination have been conducted in restricted lab settings that presumably
Biochemistry

Using formic acid, a new technique converts carbon dioxide into a useful resource for the biochemical sector.

In addition to assisting in the reduction of atmospheric carbon dioxide, new synthetic metabolic pathways for the fixation of carbon dioxide have the potential to substitute biological, carbon-neutral manufacturing processes for pharmaceuticals and active ingredients. Formic acid can be used to transform carbon dioxide into a valuable material for the biochemical industry, according to a new study that was published in Nature Communications. Carbon capture, or the sequestration of carbon dioxide from large emission sources, is an urgent issue in light of rising greenhouse gas emissions. In nature, carbon dioxide digestion has been occurring for a long period of time;
Biochemistry

A novel technique for examining protein crystals may provide new opportunities for drug discovery.

Another strategy for dissecting protein gems — created by Cornell College scientists and given an out-of-control two-section name — could open up applications for new medication revelations and different areas of biotechnology and organic chemistry. The development, which is described in a paper that was published on March 3 in Nature Communications, gives researchers the tools they need to interpret the data from X-ray crystallography experiments, which were once discarded because they were an essential method for studying the structures of proteins. A better comprehension of a protein's movement, structure, and overall function may result from this work, which builds
Biochemistry

Investigating the potential of bioflavonoids as SARS-CoV-2 inhibitors

Bioflavonoids have been investigated as potential COVID-19 inhibitors in a study published in the International Journal of Computational Biology and Drug Design. The mixtures — narirutin, naringin, neohesperidin, and hesperidin — are found in citrus organic products. It is common knowledge of their numerous therapeutic and physiological effects. The chance of reusing them despite the continuous pandemic is examined considering PC's demonstration of their association with the infection's scandalous spike protein. The SARS-CoV-2 infection enters our phones by utilizing a protein called S-protein to collaborate with a human protein called angiotensin, changing over compound 2, ACE2, present on the outer
Biochemistry

A study discovered that changing the cell membrane influences the production of amyloid-β.

LMU researchers have demonstrated in cell cultures that the addition of long-chain fatty acids can alter the activity of a crucial enzyme and thicken cell membranes. Deposits of the protein amyloid, which clumps together to form plaques in the brain, are a hallmark of Alzheimer's disease. The amyloid protein is delivered by a compound that lives in cell layers. Now, a group led by Prof. Harald Steiner and Dr. Edgar Dawkins from the Biomedical Center Munich at LMU has demonstrated that membrane thickness influences the production of amyloid. Lipid bilayers make up cell membranes. They can be thickened externally by
Biochemistry

Artificial photosynthesis for eco-friendly food production

Both protecting the environment and providing food to the world's ever-increasing population are frequently antagonistic goals. Using a form of artificial photosynthesis, researchers at the Technical University of Munich (TUM) have successfully developed a method for the synthetic production of nutritional protein. The demand for large quantities of nutritional protein, which can also be used in meat substitute products, is primarily driven by the animal feed industry. At the TUM Campus Straubing for Biotechnology and Sustainability (TUMCS), a group led by Prof. Volker Sieber was successful in producing the amino acid L-alanine—an essential protein building block—from the polluting gas CO2.
Biochemistry

New bio-inspired compounds are being developed by scientists to improve bone healing.

Osteoporosis and other diseases make it even harder for people to regenerate their bones as they get older. Researchers are looking for new treatments that make it easier for bones to grow back in order to help the aging population. Now, a group of researchers from the Max Bergmann Center for Biomaterials (MBC) and the Biotechnology Center (BIOTEC) at the Medical Faculty of the TU Dresden have created novel bio-inspired molecules that help mice regenerate their bones. The findings were presented and discussed in the journal Biomaterials. The capacity for bone regrowth declines with age. Fractures take longer to heal,
Biochemistry

The structure of the protein methyltransferase from the mpox virus has been solved by researchers.

The structure of the monkeypox virus's protein methyltransferase has been deciphered by researchers from Prague's Institute of Organic Chemistry and Biochemistry. It is with the assistance of this protein that the infection escapes human invulnerability and causes the monkeypox sickness. In view of this disclosure, they have arranged substances that can hinder the capability of methyltransferase. The findings of this study may be the first step toward developing a brand-new class of antivirals. This is true for diseases brought on by other viruses as well as monkeypox, such as COVID-19, brought on by the SARS-CoV-2 coronavirus. An article on the