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Cell & Microbiology

Cell & Microbiology

New System for Safer Gene-Drive Testing and Development is Developed by Researchers

A gene drive is a genetic technology that spreads a specific trait through a population by increasing the frequency of that trait in the gene pool. Gene drives have potential applications in controlling or eliminating pest populations, but they also raise concerns about unintended ecological consequences and ethical implications. The vast potential of CRISPR and its technological frontiers are still being explored by scientists in a variety of fields, from human health to the world's food supply. CRISPR-based gene drives, a genetic editing technique created to alter how genetic components are transferred from one generation to the next, are an
Cell & Microbiology

A study discovered that DNA repair diminishes with age, decreasing fertility.

Indeed, even worms have a ticking richness clock. More seasoned worms are less effective at fixing broken DNA strands while making egg cells, a piece of a cycle that is fundamental for richness. Another review from College of Oregon (UO) scholars proposes one potential explanation: generational change eases back with age. Scientists from the lab of Diana Libuda report the discoveries in a paper distributed Nov. 7 in PLOS Hereditary Qualities. Every sperm or egg cell has only a fraction of the chromosomes found in a normal cell.During meiosis, the cell division process that structures sperm and eggs, the parent
Cell & Microbiology

A systems investigation of renal metabolism finds surprising linkages to viral defense.

Our kidney channels 180 liters of blood consistently and holds supplements through a cycle called endocytosis and a dynamic vehicle in the kidney cells. In another global review, a worldwide group of scientists, led by Markus Rinschen from the Aarhus Foundation of Cutting Edge Examinations and the Branch of Biomedicine at Aarhus College, explored how this course of endocytosis is managed by a focal protein, the lipid kinase VPS34, in mice. This lipid kinase is engaged with the vesicular dealing and endocytic arrangement of film proteins—a cycle that is vital for the body to get the right supplements, yet in
Cell & Microbiology

Identity theft is the key to the success of a cat parasite.

The parasite Toxoplasma is carried by a huge part of the worldwide human populace. Presently, a review led by scientists at Stockholm College shows how this tiny parasite so effectively spreads in the body, for instance to the mind. The parasite taints safe cells and seizes their character. The review is distributed in the journal Cell Host and Organism. To battle diseases, the different jobs of safe cells in the body are completely managed. Researchers have long considered how Toxoplasma figures out how to taint such countless individuals and creature species and spread so effectively. "We have now found a