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Medical research

Medical research

A clinical trial has found that toothpaste containing synthetic tooth minerals can prevent cavities just as well as fluoride.

Brushing two times per day fends the dental specialist off, yet might we at any point enhance the toothpaste we use to keep up with clean teeth, keeping clinical issues that wind up from unfortunate dental wellbeing? Most toothpastes use fluoride, a useful asset for oral cleanliness. Notwithstanding, fluoride can present medical issues at times, particularly for kids who consume a lot of fluoride by gulping a large portion of their toothpaste. To avoid these issues, children typically only use a small amount of toothpaste, which reduces the effectiveness of toothbrushing. In the quest for choices, a group of global
Medical research

Study in Mice Demonstrates New Treatment is Effective for Bladder Cancer

According to a recent Northwestern Medicine study conducted in mice, an epigenetics medicine already used to treat blood malignancies and rare sarcomas can inhibit the progression of bladder cancer by stimulating the immune system. It's the first time a medication intended to treat uncommon sarcomas and hematologic malignancies has been applied to one of the most prevalent solid tumors. The drug, tazemetostat, was originally developed to treat lymphoma. “We've discovered for the first time that the drug actually works by activating the immune system, not just by inhibiting the tumor,” said lead study author Dr. Joshua Meeks, an associate professor
Medical research

Stroke medication provides neuroprotection while having no long-term influence on memory and learning.

According to a new study by researchers at the University of Colorado Anschutz Medical Campus, a promising new stroke drug that temporarily inhibits a key protein in the brain without causing lasting damage may significantly alter the treatment of cerebral and global ischemia in the future. The study was published in the Journal of Biological Chemistry in May. K. Ulrich Bayer, Ph.D., a senior author of the study and professor of pharmacology at the University of Colorado School of Medicine, stated, "We are one step closer to a new stroke therapy." Our research demonstrates that the neuroprotective effects were significant,
Medical research

Cancer cells have a remarkable ability to infiltrate deep into their surroundings, according to engineers.

In "The Princess and the Pea," a fairy tale by Hans Christian Andersen published in 1835, the princess is praised for her sensitivity to a pea positioned under 20 mattresses on her bed. A new study from the McKelvey School of Engineering at Washington University in St. Louis has discovered that unlike normal cells, which are unable to sense a layer of cells beneath the top collagen layer on which they normally travel, cancer cells are able to sense this layer, much like the fabled princess. Amit Pathak, an associate professor of mechanical engineering and materials science, and Christopher Walter,
Medical research

A probiotic company has discovered a relationship between young gut bacteria and potential centenarians.

Researchers from AIage Life Science, a probiotics manufacturer in China, looked into the microflora that lives in the guts of centenarians because there is growing scientific evidence showing how the gut microbiota affects human health. In the study, "Longevity of centenarians is reflected by the gut microbiome with youth-associated signatures," which was published in Nature Aging, the researchers looked at the microbiomes of 1,575 people ranging in age from 20 to 117, 297 of whom were reported to be 100 years of age or older. In the same journal issue, a research briefing on the study with the title "Youth-associated
Medical research

Researchers Suggest Mass Stool Sample Banking for Later Fecal Transplants

Particularly in the last few decades, changes in how humans live and eat have significantly altered the gut microbiota. Type 2 diabetes, digestive system disorders, allergies, asthma, and other ailments have all been connected to these changes. In an opinion piece that was published on June 30 in the journal Trends in Molecular Medicine, a group from Harvard Medical School and Brigham and Women's Hospital (BWH) makes the suggestion that we can reverse these trends by encouraging people to save samples of their own gut microbiota while they are still young and healthy in case they ever need them for
Medical research

Researchers Find Bacteria that were Once Thought to be Harmless can Worsen Lung Disease that Already Exists

Neisseria, a genus of bacteria found in the human body, is not as harmless as previously believed and can cause infections in people who have bronchiectasis, asthma, and chronic obstructive pulmonary disease (COPD). An international team of researchers led by Nanyang Technological University, Singapore (NTU Singapore) made this discovery. The scientists provided definitive proof that Neisseria species can infect the lungs and are connected to patients' increasing bronchiectasis (a form of lung disease) in a major study that was published today in Cell Host & Microbe. Up to 50% of Singaporean patients with bronchiectasis experience abnormal enlargement of their pulmonary
Medical research

Cuts Costs and Harms with Novel Blood Test and Image-Based Prostate Cancer Screening

According to a cost-effectiveness study from Karolinska Institutet that was published in the journal European Urology, the combination of a novel blood test and magnetic resonance imaging (MRI) can lower overdiagnosis of low-risk cancers as well as societal costs associated with prostate cancer screening. The results provide support for organized prostate cancer testing in Sweden, researchers say. A barrier to the introduction of nationwide prostate cancer screening has been that PSA (prostate-specific antigen) tests combined with traditional biopsies result in the detection of numerous minor low-risk tumors. MRI has been shown to reduce this overdiagnosis but presents a challenge due
Medical research

According to a study on metastasis, the time of day has an impact on cancer diagnosis and therapy.

Your sleeping pattern is just one aspect of your circadian rhythm; it can also affect how cancer grows, gets diagnosed, and is treated. Researchers describe how we could better time when patients are tested for cancer and when they receive therapies to improve diagnostic accuracy and treatment success in a review paper that was published in the journal Trends in Cell Biology. The paper also discusses the role of circadian rhythms in the progression and spread of tumors. The authors, molecular oncologists Zoi Diamantopoulou, Ana Gvozdenovic, and Nicola Aceto from the ETH Zurich in Switzerland, write, "The circadian rhythm governs
Medical research

AI language models have the potential to open a Pandora’s box of medical research fraud.

Clinical understudy and specialist Faisal Elali of the State College of New York Downstate Wellbeing Sciences College and clinical recorder and scientist Leena Rachid from the New York-Presbyterian/Weill Cornell Clinical Center needed to check whether computerized reasoning could compose a created research paper and afterward examine how best to distinguish it. Man-made consciousness is an undeniably important and indispensable piece of logical examination. It is utilized as an instrument to examine muddled informational collections; however, creating the real paper for publication is rarely utilized. Man-made intelligence-created research papers, then again, can look persuasive in any event when viewed in the