Our bodies have developed impressive boundaries to safeguard themselves against unfamiliar substances—from our skin, to our cells, and each part inside the cells, each piece of our bodies has defensive layers. These protections, while fundamental, represent a critical test for drug medications and treatments, for example, immunizations, that need to sidestep various obstructions to achieve their objectives. Although these obstructions are essentially significant in drug science and medication configuration, a lot is as yet unclear about them and how to conquer them. In a new report, scientists from Xi'an Jiaotong-Liverpool University and Nanjing University in China, and Western Washington and