A group led by Scripps Exploration researchers has revealed key subtleties of a safe cell process that regularly underlies extreme irritation in the body. The findings could lead to better approaches for preventing and treating irritant-related conditions such as sepsis, joint pain, and coronary vein disease. In the review, published September 21, 2022 in Nature Correspondences, the scientists showed that a multi-protein "sub-atomic machine" called WASH plays a strong part in limiting extreme fiery action by neutrophils, safe cells that are significant early responders against diseases. "Our discoveries highlight the chance of future medicines that focus on this WASH-managed pathway